Article
Induction of osteoblast differentiation phenotype on poly(L-lactic acid) nanofibrous matrix.
Biomaterials - 1 Oct 2008
Hu Jiang, Liu Xiaohua, Ma Peter X
Abstract excerpt
Thin sheets of nanofibrous (NF) poly(L-lactic acid) (PLLA) matrix were fabricated using a novel phase separation method, mimicking the structure of natural collagen fibers. In this study, the cell morphology, cytoskeleton and adhesion structure, proliferation and differentiation were investigated on NF PLLA matrix using an osteoblast cell line model. Scanning electron microscopy revealed that the MC3T3-E1 cells...
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