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Article

Expression of osteoblastic phenotype in periodontal ligament fibroblasts cultured in three-dimensional collagen gel.

Journal of applied oral science : revista FOB - 1 Jan 2000

Alves Luciana Bastos, Mariguela Viviane Casagrande, Grisi Márcio Fernando de Moraes, Souza Sérgio Luiz Scaombatti de, Novaes Junior Arthur Belém, Taba Junior Mário, Oliveira Paulo Tambasco de, Palioto Daniela Bazan

Abstract excerpt

OBJECTIVE: To investigate the influence of a three-dimensional cell culture model on the expression of osteoblastic phenotype in human periodontal ligament fibroblast (hPDLF) cultures. MATERIAL AND METHODS: hPDLF were seeded on bi-dimensional (2D) and three-dimensional (3D) collagen type I (experimental groups) and and on a plastic coverslip (control) for up to 14 days. Cell viability and alkaline phosphatase...

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Identifiers

PMID: 26018313
DOI: 10.1590/1678-775720140462
PMCID: PMC4428466

Genes

RUNX2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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