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Article

Response of bone marrow stromal cells to graded co-electrospun scaffolds and its implications for engineering the ligament-bone interface.

Biomaterials - 1 Nov 2012

Samavedi Satyavrata, Guelcher Scott A, Goldstein Aaron S, Whittington Abby R

Abstract excerpt

Biomaterial scaffolds with gradients in architecture, mechanical and chemical properties have the potential to improve the osseointegration of ligament grafts by recapitulating phenotypic gradients that exist at the natural ligament-bone (L-B) interface. Towards the larger goal of regenerating the L-B interface, this in vitro study was performed to investigate the potential of two scaffolds with mineral gradients...

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PMID: 22835644
DOI: 10.1016/j.biomaterials.2012.07.008

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