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Article

Expression of Fhit, Mlh1, p16INK4A and E-cadherin in early gastric neoplasia: Correlation with histological grade and gastric phenotype.

Oncology reports - 1 Sept 2007

Hara Akihito, Yashima Kazuo, Yasugi Akiko, Koda Masaharu, Kawaguchi Koichiro, Harada Kenichi, Andachi Hironobu, Shiota Goshi, Ito Hisao, Murawaki Yoshikazu

Abstract excerpt

An increasing number of tumor suppressor genes (TSGs) that are inactivated by hypermethylation of CpG islands in the promoter have been reported in gastric carcinomas. The aim of this study is to evaluate the clinical significance of TSG protein expression, which correlates with the promoter status, methylated or not, during the early stages of gastric carcinogenesis and to examine its relationship with mucin...

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PMID: 17671701

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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