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Article

Hypermethylation of Chfr and hMLH1 in gastric noninvasive and early invasive neoplasias.

Virchows Archiv : an international journal of pathology - 1 Feb 2005

Homma Naoyuki, Tamura Gen, Honda Teiichiro, Jin Zhe, Ohmura Kiyonari, Kawata Sumio, Motoyama Teiichi

Abstract excerpt

Human tumors are genetically unstable, and the instability exists at two distinct levels-the chromosomal level and the nucleotide level. Chfr and hMLH1 hypermethylation, which may lead to chromosomal instability (CIN) and microsatellite instability (MSI), respectively, was analyzed in gastric non...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 15735977
DOI: 10.1007/s00428-004-1146-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15735977-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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