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Article

DNA methylation profiles of differentiated-type gastric carcinomas with distinct mucin phenotypes.

Cancer science - 1 Aug 2005

Motoshita Junichi, Oue Naohide, Nakayama Hirofumi, Kuraoka Kazuya, Aung Phyu Phyu, Taniyama Kiyomi, Matsusaki Keisuke, Yasui Wataru

Abstract excerpt

Gastric carcinomas (GC) are classified into four phenotypes according to mucin expression. Previous studies revealed the association of distinct genetic profiles in GC with mucin phenotypic expression; however, the roles of epigenetic changes, such as DNA methylation, are poorly understood. We examined whether the phenotypic expression of GC was associated with DNA methylation of hMLH1, MGMT, p16(INK4a), RAR-beta...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Cyclin-Dependent Kinase Inhibitor p16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Mucins

Share to MutL Protein Homolog 1

Share to Neoplasm Proteins

Share to Receptors, Retinoic Acid

Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 16108828
DOI: 10.1111/j.1349-7006.2005.00074.x
PMCID: PMC11158929

Genes

MUC2
MGMT
CDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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