Article
Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: clinicopathologic significance and genetic background.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Nov 2006
Tajima Yusuke, Yamazaki Kimiyasu, Makino Reiko, Nishino Nobukazu, Aoki Shigeo, Kato Masanori, Morohara Koji, Kaetsu Tsutomu, Kusano Mitsuo
Abstract excerpt
PURPOSE: Gastric and intestinal phenotypic cell markers are expressed in gastric carcinomas, irrespective of their histologic type. In the present study, we determined the clinicopathologic significance of phenotypic marker expression in early-stage gastric differentiated-type tumors and the association between marker expression and genetic alterations. EXPERIMENTAL DESIGN: Phenotypic marker expression was...
Topics
- Adenoma
- Biomarkers, Tumor
- DNA Mutational Analysis
- Gastric Mucins
- Genes, APC
- Genes, p53
- Genes, ras
- Humans
- Immunohistochemistry
- Microsatellite Instability
- Microsatellite Repeats
- Mucin-2