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Article

DNA methylation of multiple genes in gastric carcinoma: association with histological type and CpG island methylator phenotype.

Cancer science - 1 Oct 2003

Oue Naohide, Oshimo Yasuhiro, Nakayama Hirofumi, Ito Reiko, Yoshida Kazuhiro, Matsusaki Keisuke, Yasui Wataru

Abstract excerpt

Hypermethylation of CpG islands is associated with silencing of various tumor suppressor genes. Recent studies on colorectal and gastric cancer have identified a CpG island methylator phenotype (CIMP), which involves the targeting of multiple genes by promoter hypermethylation. For determination of association between DNA methylation pattern or histological type and CIMP status in gastric carcinoma, CpG islands...

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Share to CpG Islands
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CDH1 gene

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Share to Promoter Regions, Genetic

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Source

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Identifiers

PMID: 14556664
DOI: 10.1111/j.1349-7006.2003.tb01373.x
PMCID: PMC11160148

Genes

CDH1
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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