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Article

Accumulation of DNA methylation is associated with tumor stage in gastric cancer.

Cancer - 15 Mar 2006

Oue Naohide, Mitani Yoshitsugu, Motoshita Junichi, Matsumura Shunji, Yoshida Kazuhiro, Kuniyasu Hiroki, Nakayama Hirofumi, Yasui Wataru

Abstract excerpt

BACKGROUND: The authors purpose in this study was to clarify the difference in terms of clinicopathologic features between gastric cancer (GC) with high numbers of DNA methylated genes and CpG island methylator phenotype (CIMP)-positive GC as originally defined. METHODS: We analyzed DNA methylation of 12 tumor-related genes (hMLH1, MGMT, p16(INK4a), CDH1, RAR-beta, HLTF, RIZ1, TM, FLNc, LOX, HRASLS, HAND1) in 75...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, Tumor Suppressor

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Share to Polymorphism, Single-Stranded Conformational

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Source

Identifiers

PMID: 16475210
DOI: 10.1002/cncr.21754

Genes

CDH1
HAND1
HLTF
LOX
MGMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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