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Article

Global DNA hypomethylation is an early event in Helicobacter pylori -related gastric carcinogenesis

26 May 2011

Abstract excerpt

AIM: Cancer, particularly gastric cancer (GC), is prevalently an epigenetic phenomenon that is dependent on an altered DNA methylation pattern. In gastric carcinogenesis, many genes show aberrant methylation; however, none of them may be used as a biomarker of cancer risk and progression. The authors aimed to evaluate the global DNA methylation of gastric mucosa in Helicobacter pylori (Hp)-related chronic...

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Identifiers

PMID: 21617174
DOI: 10.1136/jcp.2010.087858

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