Article
Comparison of the TaqMan and LightCycler systems in evaluation of CYP2B6 516G>T polymorphism.
Molecular and cellular probes - 1 Jan 2000
Chantarangsu Soranun, Cressey Tim, Mahasirimongkol Surakameth, Tawon Yardpiroon, Ngo-Giang-Huong Nicole, Jourdain Gonzague, Lallemant Marc, Chantratita Wasun
Abstract excerpt
Understanding genetically encoded inherited differences in drug metabolism and drug targets offers the promise of minimizing adverse drug reactions and improving therapies. We have compared two real-time PCR-based methods, the TaqMan and LightCycler for the pharmacogenetic evaluation of CYP2B6 516G>T polymorphism. Both methods were found to be suitable for pharmacogenetic testing of CYP2B6 516G>T in the meaning...
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