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Article

SNP genotyping using TaqMan technology: the CYP2D6*17 assay conundrum.

Scientific reports - 19 Mar 2015

Gaedigk Andrea, Freeman Natalie, Hartshorne Toinette, Riffel Amanda K, Irwin David, Bishop Jeffrey R, Stein Mark A, Newcorn Jeffrey H, Jaime Lazara Karelia Montané, Cherner Mariana, Leeder J Steven

Abstract excerpt

CYP2D6 contributes to the metabolism of many clinically used drugs and is increasingly tested to individualize drug therapy. The CYP2D6 gene is challenging to genotype due to the highly complex nature of its gene locus. TaqMan technology is widely used in the clinical and research settings for genotype analysis due to assay reliability, low cost, and the availability of commercially available assays. The assay...

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Identifiers

PMID: 25788121
DOI: 10.1038/srep09257
PMCID: PMC4365394

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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