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Article

High-speed genotyping of CYP1A2*1F mutation with fluorescent hybridization probes using the LightCycler.

Pharmacogenomics - 1 Sept 2003

Popp Johannes, Messner Barbara, Steimer Werner

Abstract excerpt

The polymorphism CYP1A2*1F of the cytochrome 1A2 gene affects the inducibility of this cytochrome, which is involved in the metabolism of many commonly used drugs. We developed a rapid-cycle polymerase chain reaction (PCR) and fluorescent probe melting curve analysis on the LightCycler instrument for identification of this mutation. This new method was confirmed by genotyping 101 samples in parallel to...

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Identifiers

PMID: 12943470
DOI: 10.1517/phgs.4.5.643.23798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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