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Article

Assay for the simultaneous detection of the 1C and 1F alleles of the CYP1A2 gene by real-time polymerase chain reaction and melting curve analysis.

Psychiatric genetics - 1 Apr 2006

Casley William L, LeBlanc-Westwood Carole A

Abstract excerpt

Pharmacogenetic variation is an important factor in the therapeutic outcome of many drug treatments. The cytochrome P450 isoform CYP1A2 is involved in the metabolism of a number of antipsychotic drugs. Variable expression of this enzyme may result in idiosyncratic drug responses, including adverse reactions. A number of DNA sequence polymorphisms have been identified in the CYP1A2 gene. Of these, two alleles,...

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PMID: 16538186
DOI: 10.1097/01.ypg.0000185030.35558.6d

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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