Article
CYP2A6 genotyping methods and strategies using real-time and end point PCR platforms.
Pharmacogenomics - 1 Jan 2016
Wassenaar Catherine A, Zhou Qian, Tyndale Rachel F
Abstract excerpt
CYP2A6 genotyping is of clinical importance--CYP2A6 gene variants influence nicotine metabolism and are associated with nicotine dependence, cigarettes per day, smoking cessation and the risk for tobacco-associated cancers. CYP2A6 gene variants also influence the metabolism of therapeutic drugs, such as the anticancer agents, tegafur and letrozole. Over the years, CYP2A6 genotyping methods have evolved to...
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