Article
Effect of the interleukin-6 C174G gene polymorphism on treatment of acute and chronic hepatitis C in human immunodeficiency virus coinfected patients.
Hepatology (Baltimore, Md.) - 1 Oct 2007
Nattermann Jacob, Vogel Martin, Berg Thomas, Danta Mark, Axel Baumgarten, Mayr Christoph, Bruno Raffaele, Tural Christina, Klausen Gerd, Clotet Bonaventura, Lutz Thomas, Grünhage Frank, Rausch Michael, Nischalke Hans Dieter, Schewe Knud, Bienek Bernhard, Haerter Georg, Sauerbruch Tilman, Rockstroh Juergen K, Spengler Ulrich
Abstract excerpt
UNLABELLED: Hepatitis C virus (HCV)/human immunodeficiency virus (HIV) coinfection poses a difficult therapeutic problem. Response to HCV-specific therapy is variable but might be influenced by host genetic factors, including polymorphisms of cytokine genes. Here, we studied whether interleukin-6 (IL-6) C174G gene polymorphism affects the response to antiviral treatment in HCV-infected HIV-positive subjects. We...
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