Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in the IFNAR1 gene in patients with chronic hepatitis C: outcome of combined IFN-alpha therapy.

European cytokine network - 1 Sept 2007

Tena-Tomás Cristina, Pedroso Maria Lucia, de Messias-Reason Iara J, Kremsner Peter G, Kun Jürgen F J

Abstract excerpt

AIMS: Interferon-alpha (IFN-alpha) alone or in combination with ribavirin has been used for the last decade in the treatment of chronic hepatitis C, although the achievement of a sustained virological response (SVR) has not been very satisfactory. The treatment outcome depends on viral genotypes and host genetic polymorphisms in genes involved in the IFN-alpha signaling cascade. In this paper, we investigated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Drug Therapy, Combination

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Viral

Share to Hepatitis C, Chronic

Share to Interferon Type I

Share to Receptor, Interferon alpha-beta

Share to Remission Induction

Share to Ribavirin

Source

Identifiers

PMID: 17823081
DOI: 10.1684/ecn.2007.0098

Genes

IFNAR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in the IFNAR1 gene in patients with chronic hepatitis C: outcome of combined IFN-alpha therapy.PMID 17823081Read ↗

Association of two variants of the interferon-alpha receptor-1 gene with the presentation of hepatitis B virus infection.Semantic proximity Read ↗

Genomic determinants of hepatitis C virus antiviral therapy outcomes: toward individualized treatment.Semantic proximity Read ↗

A non-synonymous single nucleotide polymorphism in IFNAR1 affects susceptibility to chronic hepatitis B virus infection.Semantic proximity Read ↗

Interleukin-10.rs1800896 and Interleukin-18.rs1946518 gene polymorphisms could not predict the outcome of hepatitis C virus infection in Egyptian patients treated with pegylated interferon plus ribavirin.Semantic proximity Read ↗

Genetic influence of IFN-γ gene polymorphisms on hepatitis C progression and recovery.Semantic proximity Read ↗

Genetic polymorphism of interferon-gamma, interferon-gamma receptor, and interferon regulatory factor-1 genes in patients with hepatitis B virus infection.Semantic proximity Read ↗

Impact of the IL-18 gene polymorphism in response to antiviral therapy in chronic HCV genotype 4 patients.Semantic proximity Read ↗

Association of SNPs in interferon receptor genes in chronic hepatitis C with response to combined therapy of interferon and ribavirin.Semantic proximity Read ↗

An association study of functional polymorphic genes IRF-1, IFNGR-1, and IFN-γ with disease progression, aspartate aminotransferase, alanine aminotransferase, and viral load in chronic hepatitis B and C.Semantic proximity Read ↗

Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: A pilot studySemantic proximity Read ↗

Exhaustive genotyping of the interferon alpha receptor 1 (IFNAR1) gene and association of an IFNAR1 protein variant with AIDS progression or susceptibility to HIV-1 infection in a French AIDS cohort.Semantic proximity Read ↗

The TNFA -308G>A and IL10 -1082A>G Polymorphisms as Predictive Biomarkers of Chronic HCV InfectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.