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Article

The IL6-174G/C Polymorphism Associated with High Levels of IL-6 Contributes to HCV Infection, but Is Not Related to HBV Infection, in the Amazon Region of Brazil.

Viruses - 28 Feb 2022

Queiroz Maria Alice Freitas, Santiago Angélica Menezes, Moura Tuane Carolina Ferreira, Amoras Ednelza da Silva Graça, Conde Simone Regina Souza da Silva, Cayres-Vallinoto Izaura Maria Vieira, Ishak Ricardo, Vallinoto Antonio Carlos Rosário

Abstract excerpt

The dysregulation of cytokine production can lead to an inefficient immune response, promoting viral persistence that induces the progression of chronic viral hepatitis. The study investigated the association of the IL6-174G/C polymorphism with changes in cytokine levels and its influence on the persistence and progression of chronic hepatitis caused by HBV and HCV in 72 patients with chronic hepatitis B (HBV),...

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Identifiers

PMID: 35336914
DOI: 10.3390/v14030507
PMCID: PMC8950165

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