Article
The transforming growth factor-beta high-producer genotype is associated with response to hepatitis C virus-specific therapy in HIV-positive patients with acute hepatitis C.
AIDS (London, England) - 11 Jul 2008
Nattermann Jacob, Vogel Martin, Nischalke Hans Dieter, Danta Mark, Ahlenstiel Golo, Michalk Monika, Sauerbruch Tilman, Rockstroh Jürgen K, Spengler Ulrich
Abstract excerpt
BACKGROUND: Coinfection with the hepatitis C virus (HCV) in HIV-positive patients is an emerging health problem. The factors affecting response to HCV-specific therapy are poorly understood but may involve host genetic factors. HCV NS5A-induced inhibition of transforming growth factor-beta signal...
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