Article
Association between IL7R polymorphisms and severe liver disease in HIV/HCV coinfected patients: a cross-sectional study.
Journal of translational medicine - 30 Jun 2015
Guzmán-Fulgencio María, Berenguer Juan, Jiménez-Sousa María A, Pineda-Tenor Daniel, Aldámiz-Echevarria Teresa, García-Broncano Pilar, Carrero Ana, García-Álvarez Mónica, Tejerina Francisco, Diez Cristina, Vazquez-Morón Sonia, Resino Salvador
Abstract excerpt
BACKGROUND: Interleukin-7 (IL-7) is a critical factor for T cell development and for maintaining and restoring homeostasis of mature T cells. Polymorphisms at α-chain of the IL-7 receptor (IL7R or CD127) gene are related to evolution of HIV-infection, but there are no data concerning the evolution of hepatitis C virus (HCV) infection. The aim of this study was to analyze the association between IL7R polymorphisms...
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