Article
Evidence for human DNA-mediated transfer of the suppressed phenotype into malignant Chinese hamster cells.
Oncogene - 1 Dec 1991
Schäfer R, Nirkko A C, Ambühl P M, Grzeschik K H, Schwarte-Waldhoff I
Abstract excerpt
Genetic suppression of the neoplastic phenotype has been demonstrated in somatic cell hybrids between tumor and normal cells. Suppression in whole-cell and microcell hybrids cannot, as yet, be attributed to specific elements defined at the molecular level. To identify a gene capable of suppressin...
Topics
- 3T3 Cells
- Animals
- Blotting, Southern
- Cell Division
- Cell Line
- Cell Transformation, Neoplastic
- Clone Cells
- Cloning, Molecular
- Cricetinae
- Cricetulus
- DNA
- Female
- Humans
- Mice
- Phenotype
- Placenta
- Pregnancy
- Suppression, Genetic