Article
Reduction of caveolin-1 expression in tumorigenic human cell hybrids.
Journal of biochemistry - 1 Aug 1998
Suzuki T, Suzuki Y, Hanada K, Hashimoto A, Redpath J L, Stanbridge E J, Nishijima M, Kitagawa T
Abstract excerpt
Studies on human cell hybrids of a cervical carcinoma cell line, HeLa, and normal fibroblasts have indicated that the tumorigenicity of these cells is under the control of a putative tumor suppressor on chromosome 11, although the nature of this suppressor remains unknown. We examined the expression of caveolin-1, a protein component of caveolae of the plasma membrane in these cell hybrids. The non-tumorigenic...
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