Article
The impact of HLA-A and -DRB1 on age at onset, disease course and severity in Scandinavian multiple sclerosis patients.
European journal of neurology - 1 Aug 2007
Smestad C, Brynedal B, Jonasdottir G, Lorentzen A R, Masterman T, Akesson E, Spurkland A, Lie B A, Palmgren J, Celius E G, Hillert J, Harbo H F
Abstract excerpt
The human leucocyte antigen (HLA) class II haplotype DRB1*15-DQB1*06 (DR15-DQ6) is associated with susceptibility to multiple sclerosis (MS), and HLA class I associations in MS have also been reported. However, the influence of HLA class I and II alleles on clinical phenotypes in MS has not yet b...
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