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Article

The HLA-DRB1 and HLA-DQB1 alleles are associated with multiple sclerosis disability progression in Slovak population.

Neurological research - 1 Jul 2018

Čierny Daniel, Lehotský Ján, Kantorová Ema, Sivák Štefan, Javor Juraj, Kurča Egon, Dobrota Dušan, Michalik Jozef

Abstract excerpt

OBJECTIVE: The aim of our present study was to analyse the association of HLA-DRB1 and -DQB1 alleles and genotypes with Multiple Sclerosis (MS) disability progression in a cohort of Central European Slovak population. METHODS: The allele and genotype variants were analyzed in 282 non-related MS patients. Rate of disease disability progression was evaluated using EDSS score in the 5th, 7th, 10th, and 15th year of...

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PMID: 29619906
DOI: 10.1080/01616412.2018.1456711

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