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HLA class II alleles and multiple sclerosis in Tunisian patients.

Clinical neurology and neurosurgery - 1 Dec 2010

Messadi Amira, Najiba Fekih-Mrissa, Ouerhani Slah, Zaweli Jemel, Louatti Ines, Layouni Sami, Nciri Brahim, Bouaicha Ghaya, Kouki Wafa, Yedeas Mondher, Raies Aly, Mrissa Ridha, Gritli Nasreddine

Abstract excerpt

OBJECTIVE: The aim of our study was to investigate the association of HLA-DRB1 and -DQB1 alleles with multiple sclerosis (MS) in a Tunisian population and their effect on age at onset and disease severity. METHODS: 58 MS patients and 105 healthy controls were genotyped for HLA class II alleles by PCR-SSP technique. RESULTS: An association of MS with HLA-DRB1*15 was found (14.7% vs 3.8%, OR (95% CI)=4.34...

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Identifiers

PMID: 20691532
DOI: 10.1016/j.clineuro.2010.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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