Article
The association of HLA-DRB1 and HLA-DQB1 alleles with genetic susceptibility to multiple sclerosis in the Slovak population.
Neurological research - 1 Jan 2015
Michalik Jozef, Čierny Daniel, Kantorová Ema, Kantárová Daniela, Juraj Javor, Párnická Zuzana, Kurča Egon, Dobrota Dušan, Lehotský Ján
Abstract excerpt
OBJECTIVE: The aim of the present study was to assess the association between HLA-DRB1 and -DQB1 allele groups with the genetic predisposition to multiple sclerosis (MS) in the Caucasian Central European Slovak population. METHODS: A total of 282 unrelated patients with sporadic MS were enrolled in this case-control study. HLA-DRB1 and HLA-DQB1 allele groups were genotyped using a polymerase chain reaction with...
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