Article
HLA-DRB1 and disease outcome in multiple sclerosis.
Journal of neurology - 1 Apr 2001
Weatherby S J, Thomson W, Pepper L, Donn R, Worthington J, Mann C L, Davies M B, Fryer A A, Boggild M D, Young C A, Jones P W, Strange R C, Ollier W E, Hawkins C P
Abstract excerpt
The association between susceptibility to multiple sclerosis (MS) and the class II MHC allele HLA-DRB1*15 is well established although a possible relationship between this allele and outcome in MS is less clear. HLA-DRB1 typing was performed on 375 unrelated white patients with clinically definite MS and on 367 healthy controls. Putative associations of the gene with outcome were examined by dividing patients...
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