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Article

Imputation of single-nucleotide polymorphisms in inbred mice using local phylogeny.

Genetics - 1 Feb 2012

Wang Jeremy R, de Villena Fernando Pardo-Manuel, Lawson Heather A, Cheverud James M, Churchill Gary A, McMillan Leonard

Abstract excerpt

We present full-genome genotype imputations for 100 classical laboratory mouse strains, using a novel method. Using genotypes at 549,683 SNP loci obtained with the Mouse Diversity Array, we partitioned the genome of 100 mouse strains into 40,647 intervals that exhibit no evidence of historical recombination. For each of these intervals we inferred a local phylogenetic tree. We combined these data with 12 million...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22345612
DOI: 10.1534/genetics.111.132381
PMCID: PMC3276610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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