Article
Segmental phylogenetic relationships of inbred mouse strains revealed by fine-scale analysis of sequence variation across 4.6 mb of mouse genome.
Genome research - 1 Aug 2004
Frazer Kelly A, Wade Claire M, Hinds David A, Patil Nila, Cox David R, Daly Mark J
Abstract excerpt
High-density SNP screening of panels of inbred mouse strains has been proposed as a method to accelerate the identification of genes associated with complex biomedical phenotypes. To evaluate the potential of these studies, a more detailed understanding of the fine structure of sequence variation across inbred mouse strains is needed. Here, we use high-density oligonucleotide arrays to discover an extremely dense...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
