GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis.

doi:10.1101/gr.278157.123

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GenomeMUSter mouse genetic variation service enables multitrait, multipopulation data integration and analysis.

Genome research - 7 Feb 2024

Ball Robyn L, Bogue Molly A, Liang Hongping, Srivastava Anuj, Ashbrook David G, Lamoureux Anna, Gerring Matthew W, Hatoum Alexander S, Kim Matthew J, He Hao, Emerson Jake, Berger Alexander K, Walton David O, Sheppard Keith, El Kassaby Baha, Castellanos Francisco, Kunde-Ramamoorthy Govindarajan, Lu Lu, Bluis John, Desai Sejal, Sundberg Beth A, Peltz Gary, Fang Zhuoqing, Churchill Gary A, Williams Robert W, Agrawal Arpana, Bult Carol J, Philip Vivek M, Chesler Elissa J

Abstract excerpt

Hundreds of inbred mouse strains and intercross populations have been used to characterize the function of genetic variants that contribute to disease. Thousands of disease-relevant traits have been characterized in mice and made publicly available. New strains and populations including consomics, the collaborative cross, expanded BXD, and inbred wild-derived strains add to existing complex disease mouse models,...

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PMID: 38290977
DOI: 10.1101/gr.278157.123
PMCID: PMC10903950

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