Article
On the subspecific origin of the laboratory mouse.
Nature genetics - 1 Sept 2007
Yang Hyuna, Bell Timothy A, Churchill Gary A, Pardo-Manuel de Villena Fernando
Abstract excerpt
The genome of the laboratory mouse is thought to be a mosaic of regions with distinct subspecific origins. We have developed a high-resolution map of the origin of the laboratory mouse by generating 25,400 phylogenetic trees at 100-kb intervals spanning the genome. On average, 92% of the genome is of Mus musculus domesticus origin, and the distribution of diversity is markedly nonrandom among the chromosomes....
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