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Article

Role of alpha1beta1-integrin in arterial stiffness and angiotensin-induced arterial wall hypertrophy in mice.

American journal of physiology. Heart and circulatory physiology - 1 Oct 2007

Louis Huguette, Kakou Augustine, Regnault Veronique, Labat Carlos, Bressenot Aude, Gao-Li Jacqueline, Gardner Humphrey, Thornton Simon N, Challande Pascal, Li Zhenlin, Lacolley Patrick

Abstract excerpt

We examined the arterial phenotype of mice lacking alpha(1)-integrin (alpha(1)(-/-)) at baseline and after 4 wk of ANG II or norepinephrine (NE) administration. Arterial mechanical properties were determined in the carotid artery (CA). Integrin expression, MAPK kinases, and focal adhesion kinase (FAK) were assessed in the aorta. No change in arterial pressure was observed in alpha(1)(-/-) mice. Elastic...

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PMID: 17660399
DOI: 10.1152/ajpheart.00299.2007

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ANG

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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