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Article

Collagen Receptor Integrins: Rising to the Challenge

30 Jan 2008

Abstract excerpt

Integrins are alphabeta heterodimeric receptors that connect the extracellular environment with intracellular signaling events. Integrins are important for normal development and function, but are also involved in the pathogenesis of diseases including cancer, autoimmunity and heart disease. We will review the present data on a family of integrins, the collagen receptors that include the alpha1beta1, alpha2beta1,...

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PMID: 18288965
DOI: 10.2174/138945008783502494

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