Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2005

Rolf Julia, Motta Vinicius, Duarte Nadia, Lundholm Marie, Berntman Emma, Bergman Marie-Louise, Sorokin Lydia, Cardell Susanna L, Holmberg Dan

Abstract excerpt

The NOD mouse is an important experimental model for human type 1 diabetes. T cells are central to NOD pathogenesis, and their function in the autoimmune process of diabetes has been well studied. In contrast, although recognized as important players in disease induction, the role of B cells is not clearly understood. In this study we characterize different subpopulations of B cells and demonstrate that marginal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Antigens, CD1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antigens, CD1d

Share to B-Lymphocyte Subsets

Share to Diabetes Mellitus, Type 1

Share to Mice, Inbred NOD

Share to Spleen

Share to T-Lymphocytes

Source

Identifiers

PMID: 15814708
DOI: 10.4049/jimmunol.174.8.4821

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The enlarged population of marginal zone/CD1d(high) B lymphocytes in nonobese diabetic mice maps to diabetes susceptibility region Idd11.PMID 15814708Read ↗

Idd13 is involved in determining immunoregulatory DN T-cell number in NOD mice.Semantic proximity Read ↗

The idd4 locus displays sex-specific epistatic effects on type 1 diabetes susceptibility in nonobese diabetic mice.Semantic proximity Read ↗

Low rate of proliferation in immature thymocytes of the non-obese diabetic mouse maps to the Idd6 diabetes susceptibility region.Semantic proximity Read ↗

THE NOD MOUSE: A Model of Immune DysregulationSemantic proximity Read ↗

Genetic control of murine invariant natural killer T cells maps to multiple type 1 diabetes regions.Semantic proximity Read ↗

An update on the use of NOD mice to study autoimmune (Type 1) diabetes.Semantic proximity Read ↗

The Idd6.2 diabetes susceptibility region controls defective expression of the Lrmp gene in nonobese diabetic (NOD) mice.Semantic proximity Read ↗

Molecular phenotyping of immune cells from young NOD mice reveals abnormal metabolic pathways in the early induction phase of autoimmune diabetes.Semantic proximity Read ↗

Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice: identification of two potential candidate subloci.Semantic proximity Read ↗

NOD mice and autoimmunity.Semantic proximity Read ↗

Idd9.2 and Idd9.3 protective alleles function in CD4+ T-cells and nonlymphoid cells to prevent expansion of pathogenic islet-specific CD8+ T-cells.Semantic proximity Read ↗

A locus on mouse chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.