Article
Ventral abdominal wall dysmorphogenesis of Msx1/Msx2 double-mutant mice.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology - 1 May 2005
Ogi Hidenao, Suzuki Kentaro, Ogino Yukiko, Kamimura Mika, Miyado Mami, Ying Xu, Zhang Zunyi, Shinohara Masanori, Chen Yiping, Yamada Gen
Abstract excerpt
Msx1 and Msx2 genes encode the homeodomain transcription factors. Several gene knockout mice and expression studies suggest that they possess functionally redundant roles in embryogenesis. In this study, we revealed that Msx1 and Msx2 were expressed during ventral body wall formation in an overlapping manner. Msx1/Msx2 double-mutant mice displayed embryonic abdominal wall defects with disorganized muscle layers...
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