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Article

A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3.

Proceedings of the National Academy of Sciences of the United States of America - 8 Jan 2002

Nagy Peter L, Griesenbeck Joachim, Kornberg Roger D, Cleary Michael L

Abstract excerpt

Histone methylation has emerged as an important mechanism for regulating the transcriptional accessibility of chromatin. Several methyltransferases have been shown to target histone amino-terminal tails and mark nucleosomes associated with either euchromatic or heterochromatic states. However, the biochemical machinery responsible for regulating histone methylation and integrating it with other cellular events...

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PMID: 11752412
DOI: 10.1073/pnas.221596698
PMCID: PMC117519

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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A trithorax-group complex purified from Saccharomyces cerevisiae is required for methylation of histone H3.PMID 11752412Read ↗

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