Article
Modeling recurrent DNA copy number alterations in array CGH data.
Bioinformatics (Oxford, England) - 1 Jul 2007
Shah Sohrab P, Lam Wan L, Ng Raymond T, Murphy Kevin P
Abstract excerpt
MOTIVATION: Recurrent DNA copy number alterations (CNA) measured with array comparative genomic hybridization (aCGH) reveal important molecular features of human genetics and disease. Studying aCGH profiles from a phenotypic group of individuals can determine important recurrent CNA patterns that suggest a strong correlation to the phenotype. Computational approaches to detecting recurrent CNAs from a set of aCGH...
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