Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Integrating copy number polymorphisms into array CGH analysis using a robust HMM

15 Jul 2006

Abstract excerpt

MOTIVATION: Array comparative genomic hybridization (aCGH) is a pervasive technique used to identify chromosomal aberrations in human diseases, including cancer. Aberrations are defined as regions of increased or decreased DNA copy number, relative to a normal sample. Accurately identifying the locations of these aberrations has many important medical applications. Unfortunately, the observed copy number changes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Genomic variations and chromosomal abnormalities
Share to Prenatal Screening and Diagnostics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16873504
DOI: 10.1093/bioinformatics/btl238

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Integrating copy number polymorphisms into array CGH analysis using a robust HMMPMID 16873504Read ↗

GPHMM: an integrated hidden Markov model for identification of copy number alteration and loss of heterozygosity in complex tumor samples using whole genome SNP arrays.Semantic proximity Read ↗

Learning smoothing models of copy number profiles using breakpoint annotationsSemantic proximity Read ↗

CopyMap: localization and calling of copy number variation by joint analysis of hybridization data from multiple individuals.Semantic proximity Read ↗

Fast Bayesian Inference of Copy Number Variants using Hidden Markov Models with Wavelet CompressionSemantic proximity Read ↗

Modeling recurrent DNA copy number alterations in array CGH data.Semantic proximity Read ↗

Distinguishing somatic and germline copy number events in cancer patient DNA hybridized to whole-genome SNP genotyping arrays.Semantic proximity Read ↗

CGHweb: a tool for comparing DNA copy number segmentations from multiple algorithmsSemantic proximity Read ↗

HMM-DM: identifying differentially methylated regions using a hidden Markov modelSemantic proximity Read ↗

Reconstructing DNA copy number by joint segmentation of multiple sequences.Semantic proximity Read ↗

Sequential model selection-based segmentation to detect DNA copy number variation.Semantic proximity Read ↗

MixHMM: inferring copy number variation and allelic imbalance using SNP arrays and tumor samples mixed with stromal cells.Semantic proximity Read ↗

Simple binary segmentation frameworks for identifying variation in DNA copy number.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.