Article
Evaluation of Apolipoprotein-A1 genetic polymorphisms as biomarkers for Chagas cardiomyopathy in patients from Córdoba, Argentina.
Molecular biology reports - 1 Dec 2025
Velázquez López Daniela A, Blasco Romina L, Fernández Spector Hugo M, Gómez Daniela S, Sacks Amina, Montamat Mariana S, Rivarola H Walter, Chiappero Marina, Báez Alejandra L, Lo Presti M Silvina
Abstract excerpt
BACKGROUND: Chagas disease frequently leads to chronic chagasic cardiomyopathy, a major cause of mortality in endemic regions. Host genetic factors could potentially play a role in the progression of heart disease. This study aimed to assess the association between APOA1 polymorphisms and chagasic cardiomyopathy. METHODS AND RESULTS: A retrospective, observational study was conducted on 158 Trypanosoma...
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