Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in the chemokines and chemokine receptors in Chagas disease.

Human immunology - 1 Aug 2012

Flórez Oscar, Martín Javier, González Clara Isabel

Abstract excerpt

Clinical symptoms of Chagas' disease occur in 30% of the individuals infected with Trypanosoma cruzi and are characterised by heart inflammation and dysfunction. Chemokines and chemokine receptors control the migration of leukocytes during the inflammatory process and are involved in the modulation of Th1 or Th2 responses. To determine their influence, we investigated the possible role of CCL5/RANTES and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Chagas Cardiomyopathy
Share to Chemokine CCL5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-8

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, CCR2

Share to Receptors, CCR5

Share to Trypanosoma cruzi

Source

Identifiers

PMID: 22537745
DOI: 10.1016/j.humimm.2012.04.005

Genes

CCR5
CCL5
CCR2
CXCL8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in the chemokines and chemokine receptors in Chagas disease.PMID 22537745Read ↗

Genetic Polymorphism at CCL5 Is Associated With Protection in Chagas' Heart Disease: Antagonistic Participation of CCR1+ and CCR5+ Cells in Chronic Chagasic Cardiomyopathy.Semantic proximity Read ↗

Genetic susceptibility to Chagas disease cardiomyopathy: involvement of several genes of the innate immunity and chemokine-dependent migration pathways.Semantic proximity Read ↗

The role of CCR5 in Chagas disease - a systematic review.Semantic proximity Read ↗

Role of the IFNG +874T/A polymorphism in Chagas disease in a Colombian population.Semantic proximity Read ↗

Chemokine receptor CCR5 polymorphisms and Chagas' disease cardiomyopathy.Semantic proximity Read ↗

SNP/haplotype associations of CCR2 and CCR5 genes with severity of chagasic cardiomyopathy.Semantic proximity Read ↗

Interleukin 4, interleukin 4 receptor-α and interleukin 10 gene polymorphisms in Chagas disease.Semantic proximity Read ↗

Polymorphisms of toll-like receptor 2 and 4 genes in Chagas disease.Semantic proximity Read ↗

Genetic Susceptibility to Cardiac and Digestive Clinical Forms of Chronic Chagas Disease: Involvement of the CCR5 59029 A/G Polymorphism.Semantic proximity Read ↗

Role of chemokines polymorphisms in diseases.Semantic proximity Read ↗

Genetic susceptibility to Chagas disease: an overview about the infection and about the association between disease and the immune response genes.Semantic proximity Read ↗

Ex vivo T-lymphocyte chemokine receptor phenotypes in patients with chronic Chagas disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.