Article
Antigen-presenting cell population dynamics during murine silicosis.
American journal of respiratory cell and molecular biology - 1 Dec 2007
Beamer Celine A, Holian Andrij
Abstract excerpt
Silicosis is an occupational lung disease resulting from the inhalation of silica particles over prolonged periods of time, which causes chronic inflammation and progressive pulmonary fibrosis. Alveolar macrophages (AM) are critical effector cells, while less is known about the role and function of pulmonary dendritic cells (DC) in silicosis. We hypothesize that a balance exists between the suppressive nature of...
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