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Article

Asbestos and silica-induced changes in human alveolar macrophage phenotype.

Environmental health perspectives - 1 Sept 1997

Holian A, Uthman M O, Goltsova T, Brown S D, Hamilton R F

Abstract excerpt

The mechanism by which fibrogenic particulates induce inflammation that can progress to lung fibrosis is uncertain. The alveolar macrophage (AM) has been implicated in the inflammatory process because of its function and reported release of inflammatory mediators when isolated from fibrotic patients. It has been recently shown that fibrogenic, but not nonfibrogenic, particulates are highly potent in inducing...

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Identifiers

PMID: 9400713
DOI: 10.1289/ehp.97105s51139
PMCID: PMC1470149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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