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Article

Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis.

PloS one - 1 Jan 2017

McDonald Lindsay T, Johnson Sara D, Russell Dayvia L, Young M Rita I, LaRue Amanda C

Abstract excerpt

Micro-injuries associated with chronic inhaled particle exposures are linked with activation of the immune response and are thought to contribute to progression of fibrotic disease. In the pulmonary environment, we have previously demonstrated a heterogeneous population of circulating fibroblast precursors (CFPs), which are defined by expression of the pan-leukocyte marker CD45 and the collagen receptor,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28700752
DOI: 10.1371/journal.pone.0180724
PMCID: PMC5507261

Genes

CFP
DDR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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