Developmental Immunotoxicity of Low-dose Inorganic Arsenic Reprograms Macrophages Inducing Tumor-promoting Phenotypes

Abstract excerpt

In many regions around the world, including the United States, inorganic arsenic (iAs) contaminates groundwater used for drinking, food production, and irrigation. Although the World Health Organization has set a safety limit of 10 µg/L for arsenic in drinking water, an estimated 200 million people worldwide are still exposed to arsenic concentrations above this threshold. Eliciting a broad range of adverse health...

Topics

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• Arsenic
• Cell Differentiation
• Cytokines
• Macrophages
• Mice
• Mice, Inbred C57BL
• Phenotype
• RAW 264.7 Cells

Identifiers and source

Literature Corpus work

57f1daa2-74ce-519c-a621-4cafe7c43a15

DOI

10.1101/2025.07.14.663593