Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interferon-gamma production by specific lung lymphocyte phenotypes in silicosis in mice.

American journal of respiratory cell and molecular biology - 1 Apr 2000

Davis G S, Pfeiffer L M, Hemenway D R

Abstract excerpt

We recently described overproduction of interferon (IFN)-gamma by lung lymphocytes in mice with silicosis (11% of cells in air-control versus 19% of cells from silica-exposed mice; Davis and colleagues, Am. J. Respir. Cell Mol. Biol. 1999;20:813-824). We hypothesized that the increased IFN-gamma production might be due to selective enrichment of one lymphocyte phenotype. To test this hypothesis, small mononuclear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antigens, Surface
Share to Brefeldin A
Share to Interferon-gamma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Killer Cells, Natural

Share to Lymphocyte Subsets

Share to Macrophage Activation

Share to Mice, Inbred C3H

Share to Silicon Dioxide

Source

Identifiers

PMID: 10745030
DOI: 10.1165/ajrcmb.22.4.3599

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon-gamma production by specific lung lymphocyte phenotypes in silicosis in mice.PMID 10745030Read ↗

Comparative RNA‐Seq transcriptome analysis on silica induced pulmonary inflammation and fibrosis in mice silicosis modelSemantic proximity Read ↗

Functional Characterization of T Cell Populations in a Mouse Model of Chronic Obstructive Pulmonary DiseaseSemantic proximity Read ↗

Type I IFN signaling triggers immunopathology in tuberculosis‐susceptible mice by modulating lung phagocyte dynamicsSemantic proximity Read ↗

Antigen-presenting cell population dynamics during murine silicosis.Semantic proximity Read ↗

Re-appraising the role of T-cell derived interferon gamma in restriction of <i>Mycobacterium tuberculosis</i> in the murine lungSemantic proximity Read ↗

Human lung γδ T cells maintain functionality during inflammatory lung diseaseSemantic proximity Read ↗

Apoptosis Underlies Immunopathogenic Mechanisms in Acute SilicosisSemantic proximity Read ↗

Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis.Semantic proximity Read ↗

Crystalline silica-induced recruitment and immuno-imbalance of CD4 + Tissue Resident Memory T cells promote the progression of silicosis.Semantic proximity Read ↗

Silica-induced chronic inflammation promotes lung carcinogenesis in the context of an immunosuppressive microenvironment.Semantic proximity Read ↗

Enrichment of Innate Lymphoid Cell Populations in Gingival Tissue.Semantic proximity Read ↗

Multiple defects of immune cell function in mice with disrupted interferon-gamma genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.