Article
Identification and Characterization of a Dendritic Cell Precursor in Parenchymal Lung Tissue.
American journal of respiratory cell and molecular biology - 1 Mar 2017
von Garnier Christophe, Blank Fabian, Rothen-Rutishauser Barbara, Goethert Joachim R, Holt Patrick G, Stumbles Philip A, Strickland Deborah H
Abstract excerpt
The pulmonary parenchymal and mucosal microenvironments are constantly exposed to the external environment and thus require continuous surveillance to maintain steady-state immunological homeostasis. This is achieved by a mobile network of pulmonary dendritic cells (DC) and macrophages (mø) that constantly sample and process microenvironmental antigens into signals that can initiate or dampen inflammation, either...
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