Article
Hippocampal alpha 5 subunit-containing GABA A receptors are involved in the development of the latent inhibition effect.
Neurobiology of learning and memory - 1 Feb 2008
Gerdjikov T V, Rudolph U, Keist R, Möhler H, Feldon J, Yee B K
Abstract excerpt
Hippocampal GABA(A) receptors containing the alpha 5 subunit have been implicated in the modulation of hippocampal-dependent learning, presumably via their tonic inhibitory influence on hippocampal glutamatergic activity. Here, we examined the expression of latent inhibition (LI)--a form of selective learning that is sensitive to a number of manipulations targeted at the hippocampal formation, in alpha 5(H105R)...
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