Article
Tonic inhibition in principal cells of the amygdala: a central role for α3 subunit-containing GABAA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 20 Jun 2012
Marowsky Anne, Rudolph Uwe, Fritschy Jean-Marc, Arand Michael
Abstract excerpt
GABAergic inhibition in the amygdala is essential in regulating fear and anxiety. Although fast "phasic" inhibition arising through the activation of postsynaptic GABA(A) receptors (GABA(A)Rs) has been well described in the amygdala, much less is known about extrasynaptic GABA(A)Rs mediating persistent or tonic inhibition and regulating neuronal excitability. Here, we recorded tonic currents in the basolateral...
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