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Article

DNase Sda1 provides selection pressure for a switch to invasive group A streptococcal infection.

Nature medicine - 1 Aug 2007

Walker Mark J, Hollands Andrew, Sanderson-Smith Martina L, Cole Jason N, Kirk Joshua K, Henningham Anna, McArthur Jason D, Dinkla Katrin, Aziz Ramy K, Kansal Rita G, Simpson Amelia J, Buchanan John T, Chhatwal Gursharan S, Kotb Malak, Nizet Victor

Abstract excerpt

Most invasive bacterial infections are caused by species that more commonly colonize the human host with minimal symptoms. Although phenotypic or genetic correlates underlying a bacterium's shift to enhanced virulence have been studied, the in vivo selection pressures governing such shifts are po...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17632528
DOI: 10.1038/nm1612

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17632528-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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