Article
Serotype M3 and M28 Group A Streptococci Have Distinct Capacities to Evade Neutrophil and TNF-α Responses and to Invade Soft Tissues.
PloS one - 1 Jan 2015
Stetzner Zachary W, Li Dengfeng, Feng Wenchao, Liu Mengyao, Liu Guanghui, Wiley James, Lei Benfang
Abstract excerpt
The M3 Serotype of Group A Streptococcus (GAS) is one of the three most frequent serotypes associated with severe invasive GAS infections, such as necrotizing fasciitis, in the United States and other industrialized countries. The basis for this association and hypervirulence of invasive serotype M3 GAS is not fully understood. In this study, the sequenced serotype M3 strain, MGAS315, and serotype M28 strain,...
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